Turmeric Extract May Prevent, Even Reverse Diabetes – both Type 1 and 2

Turmeric Extract May Prevent, Even Reverse Diabetes (Type 1 and 2)

What if the long sought after “cure” for diabetes was as safe, affordable, and accessible as a spice sitting in your kitchen cupboard?

Leave your drugs in the chemist’s pot if you can cure the patient with food.”

-Hippocrates, 420 BC

Slowly but surely the world is waking up to the reality that diabetes is not only a preventable but  reversible, and that the drug-based model of symptom suppression and disease management has fatal flaws. For instance, some of the drugs used to treat type 2 diabetes actually increase the risk of death, with a recent study showing GMO insulin given to type 2 diabetics may lead to the development of so-called “double diabetes“: type 2 and type 1 diabetes, together. Clearly, if medicine can’t at least abide by its founding principle to “do no harm,” it must seek the answer somewhere other than from the “chemist’s pot.”

There are now thousands of studies on hundreds of natural substances and therapeutic activities that may treat blood sugar disorders and their complications.

While plants like cinnamon and gymnema sylvestre have received plenty of attention for diabetes over the years, one special plant extract that is beginning to stand out from the crowd as being exceptionally valuable as an anti-diabetic agent is turmeric.

Turmeric’s primary polyphenol curcumin is the main compound in the plant that has been researched for it’s blood sugar regulating properties. One particularly striking study, published in the American Diabetic Association’s own journal, Diabetes Care, found turmeric extract to be 100% effective in preventing pre-diabetics from developing type 2 diabetesa feat of prevention that no FDA approved drug for type 2 diabetes has yet come even close to accomplishing.

Turmeric Extract May Reverse Pancreatic Damage In Type 1 Diabetes

 Pre-clinical research now reveals it may have a role in reversing pancreatic damage in insulin-dependent, type 1 diabetics, who are routinely told that their condition can not be cured. 

Back in 2013, an exciting study published in the journal Diabetology & Metabolic Syndrome titled, “The effect of a novel curcumin derivative on pancreatic islet regeneration in experimental type-1 diabetes in rats (long term study),” found that diabetic rats who received a  curcumin derivative orally for 40 days showed an improvement of their plasma glucose, insulin and C-peptide (a marker for the health and insulin producing capability of the beta cells) levels, that began after about 4 months, and continued to improve until the 10 month mark, when their values were almost completely normalized and evidence of significant pancreatic regeneration could be observed. The researchers concluded the novel curcumin derivative (NCD): “…possesses antidiabetic actions and enhanced pancreatic islets regeneration.”

figure 2Plasma C peptide

The daily dose used in this rodent study (80 mg/kg) was the body weight equivalent of 6,400 mg or 6.4 grams of curcumin for an average North American male adult (80 kilograms). Rodent and human physiology is, of course, radically different, but significant crossovers nonetheless do exist. In another article, titled “Why Turmeric May Be the Diseased Liver’s Best Friend,” we reviewed research indicating that turmeric may help to reverse damage in and even regenerate the diabetic liver, as well as safety literature on what is a safe human dose: 

A 2001 study in cancer patients reported that quantities of curcumin up to 8 g, administered per day for three months, were not toxic and resulted in significant anti-cancer properties in a number of those treated. Turmeric is only 3-4% curcumin by weight.

Given that organ transplantation (pancreatic islet transplants) is exceedingly expensive and prohibitive due to a lack of donor material and the potential for rejection by the host, the notion that a safe, affordable, and non-prescription spice extract like curcumin may have significant therapeutic value and may even regenerate damaged pancreatic tissue, is truly exciting. That said, it should be noted that since curcumin is not patentable, it is unlikely the 800 million dollars or more needed to fund the requisite clinical trials needed to obtain FDA drug approval will materialize. Because the so-called “evidence” needed to justify the use of a new treatment is locked behind an insurmountably high paywall, don’t count on randomized, controlled, trials being performed on this “natural cure” in the near or distant future.

Curcumin’s  benefit in type 1 diabetes, also known as autoimmune diabetes, appears to be based on it reducing the activity of the host immune system in attacking self.

As the research continues to accumulate on the value of natural substances for disease prevention and treatment, it is clear the future of medicine will rely on returning to the wisdom of the ancients, where Hippocrates’ fundamental principle that one can “cure the patient with food” is once again passionately embraced.

It is indeed simple to Stay Healthy!

 

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